St. Réginos was born in Livadeia in central Greece, in the late 3rd century to Christian parents, who instilled in him the love of virtue and zeal for truth. When the old Bishop of Skopelos passed away, Saint Réginos was acclaimed as the new Bishop by all of the people. As the Arian heresy continued to rage after the Council of Nicaea (325), a new council was called at Sardica (now Sofia, Bulgaria) in 343, during which St. Réginos distinguished himself by his ability to refute the heretics.
In the year 361 a persecution broke out against the Christians under Emperor Julian the Apostate. The Prefect of Greece had Bishop Reginos and other prominent Christians arrested. The Prefect alternated between words of flattery and threats to try to persuade the Bishop to deny the Lord Jesus, thinking that by his conversion to paganism many would follow. However, all this was done in vain, for it only increased his zeal to remain steadfast in the truth. Seeing his resolve, the Prefect had Bishop Reginos beheaded on February 25, 362.
He is commemorated on February 25, which is a local holiday on the island of Skopelos . At the Monastery of Saint Réginos, which houses the relics of the saint, thousands of faithful gather each year on February 25 from the surrounding islands of Skiathos and Alonissos as well as from the coastal port city of Volos, to pay homage to the martyr. The saint has shown his love for his flock by performing several miracles of healing according to the locals, several of which name their children after him (Réginos or Regina).The beheading of St. Réginos the Martyr