St. Panteleimon had been educated as a physician, and he "dedicated his life to the suffering, the sick, the unfortunate and the needy. He treated all those who turned to him without charge, healing them in the name of Jesus Christ. He visited those held captive in prison. These were usually Christians, and he healed them of their wounds. In a short time, reports of the charitable physician spread throughout the city. Forsaking the other doctors, the inhabitants began to turn only to St. Panteleimon.
Other physicians brought his case before the Emperor Maximian. St. Panteleimon confessed to being a Christian and refused to offer sacrifice to the state gods."[He] suggested that a sick person, for whom the doctors held out no hope, should be brought before the emperor. Then the doctors could invoke their gods, and Panteleimon would pray to his God to heal the man. A man paralyzed for many years was brought in, and pagan priests who knew the art of medicine invoked their gods without success. Then, before the very eyes of the emperor, the saint healed the paralytic by calling on the name of Jesus Christ. The ferocious Maximian executed the healed man, and gave St. Panteleimon over to fierce torture.
Hermolaus, Hermippus, and Hermocrates were brought forth; they confessed and were beheaded. Throughout the many tortures, St. Panteleimon remained untouched. Enraged, Maximian ordered that St. Panteleimon be beheaded. The soldiers took him to an olive tree, but when they struck him while he was praying, the sword melted like wax. After he finished his prayer, "a Voice was heard from Heaven, calling the passion-bearer by his new name and summoning him to the heavenly Kingdom." He instructed the soldiers to rise from their knees where they had fallen in fear and to complete the execution. After they followed his instruction, the olive tree became covered with fruit.
St. Panteleimon relics at The Holy Monastery of the Great Martyr Saint Panteleimon:
Holy Great-Martyr and Healer Panteleimon,
thou imitator of God's mercy!
Look down in thy loving kindness and hearken unto us, sinners,
who offer heartfelt prayers before thy holy icon.
Ask for us from the Lord God,
before Whom the Angels stand in heaven,
remission of our sins and transgressions.
Heal the ills of body and soul of the servants of God whom we here commemorate,
who are here present,
and of all Orthodox Christians who seek thy help.
For behold, we, who because of our sins are possessed by bitter ills and have no help or consolation,
yet flee to thee for refuge, since thou hast been given Grace to pray for us and to heal every ill and every disease.
Grant, therefore, to all of us, by thy holy prayers,
health and strength of soul and body,
a good growth in the Faith and in devotion,
and all that is needful unto this temporal life and unto our salvation:
So that, having been granted great and rich mercy thorugh thee,
we may glorify thee and Him that bestoweth all good things,
our God Who is wondrous in His Saints,
the Father, and the Son, and the Holy Spirit.
From "Polny Sbornik Molitv", pp. 214-215: Prayer 3.